منابع مشابه
Th Subset Balance in Lupus Nephritis
Lupus nephritis, which has various histological patterns and variable clinical outcomes, is one of the most important complications of systemic lupus nephritis (SLE). This pathogenetic mechanism in each histologically different type of lupus nephritis (LN) remains unclear. Although SLE is suggested to be a Th2-driven disease, elevation of both Th1 and Th2 cytokines occurs in both humans and mic...
متن کاملThe prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
متن کاملCytokine balance in kidney tissue from lupus nephritis patients.
OBJECTIVE To identify the balance of Th1/Th2 cytokine expression in the kidney and evaluate the difference in cytokine balance between patients with lupus nephritis WHO classes IV and V. METHODS The expression of the CD40 molecule on cultured human mesangial cells was assessed by flow cytometry after stimulation with interferon gamma (IFN-gamma) or other cytokines. Frozen sections of kidney t...
متن کاملChemokines in lupus nephritis.
Lupus nephritis is a common solid organ manifestation of systemic lupus erythematosus (SLE). The disease is tightly linked to the production of autoantibodies and circulating immune complexes, i.e. immune complex glomerulonephritis. In this process chemokines mediate multiple biological effects, e.g. orchestrating proinflammatory microenvironments, the recruitment of immune cell subsets into th...
متن کاملLupus nephritis in children.
OBJECTIVE To determine the clinicopathological pattern of lupus nephritis in paediatric nephrology patients. DESIGN Case series study. PLACE AND DURATION OF STUDY The department of paediatric nephrology at the Children's Hospital and Institute of Child Health, Lahore, Pakistan, over a period of five years from January 2001 to December 2005. PATIENTS AND METHODS Twenty six patients upto th...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2011
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2011/980286